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Posts tagged ‘travel’

USDA–Iowa State University Lab-Engineer New Chimeric Bird Flu Viruses That Bind to Human Breast Tissue: ‘Journal of Dairy Science’


Mutant virus also binds to the milk-producing tissues of cattle, pigs, sheep, goats, and alpacas.

In a federally funded experiment conducted by Iowa State University and the USDA Agricultural Research Service, researchers created genetically engineered, chimeric H5N1 influenza viruses using reverse genetics.

They demonstrated that these lab-built viruses possess the ability to bind to the mammary-gland tissue of cattle, pigs, sheep, goats, alpacas, and—critically—to human breast epithelium containing the receptors needed for viral attachment.


Construction of the Engineered H5N1 Viruses

The foundation of this study is not observation of natural viruses, but the deliberate engineering of new viral constructs.

Lab-Built Virus : Reverse-Engineered H5N1–PR8 Chimera

The team constructed a synthetic H5N1 influenza virus consisting of:

  • An engineered low-pathogenicity 2.3.4.4b H5 (polybasic cleavage site removed),
  • Wild-type N1, and
  • Six internal gene segments from the PR8 A/Puerto Rico/8/1934 (H1N1) laboratory backbone.

The paper describes it plainly:

“A reverse engineered… H5N1 that contained an engineered low pathogenicity 2.3.4.4b H5… wild type N1, and 6 internal segments from A/Puerto Rico/8/1943 (H1N1)… .”

This is a designed chimeric virus, intentionally altered for experimental use.

Lab-Built Virus : Twist-Biosciences HA/NA Recombinant

For replication and confirmation, the team constructed a second engineered H5N1, using:

  • Synthetic HA and NA genes ordered from Twist Biosciences,
  • Combined with the same PR8 internal gene cassette.

The paper states:

“These 2 plasmids were then combined with reverse genetic plasmids encoding the 6 internal genes of the laboratory-adapted A/Puerto Rico/8/34 (H1N1).”

The study is fundamentally about manufacturing H5N1 hybrids, not characterizing natural spillover.

What the Engineered Viruses Did—Traits of the Constructs They Built

Everything that follows is a property of the viruses they created.

These outcomes describe what the engineered constructs were capable of, not what wild H5N1 has proven to do.

The Engineered Viruses Bound to Human Breast Tissue

When the researchers exposed their synthetic H5N1 to human breast sections, the virus demonstrated binding to multiple epithelial regions.

This is possible because human breast ducts and alveoli contain both avian-type (α2,3) and human-adapted (α2,6) influenza receptors, which the engineered virus exploited:

“Human sections of the interlobular duct and secretory alveoli (Ciii, Diii, Giii, and Hiii) showed multifocal to diffuse apical epithelial labeling for both SNA and MAL-II. Teat and gland cistern are uncommon in the human breast.”

Thus, the lab-built virus displayed binding compatibility with human mammary epithelium.

b. The Engineered Viruses Bound to Livestock Mammary Glands Across Species

The engineered H5N1 constructs also bound strongly to:

  • Cattle
  • Sheep
  • Goats
  • Pigs
  • Alpacas

“The current study showed that the mammary tissues from ruminants (cattle, sheep, and goat) and nonruminants (alpaca, pig, and human) exhibited labeled SA α2,3-gal and SA α2,6-gal receptors along the mammary epithelium, suggesting that both mammalian and avian IAV have the potential to bind.”

The Engineered Viruses Exhibit Mammary Tropism

The results show that the viruses they designed can attach throughout the entire mammary architecture:

  • Teat canal
  • Gland cistern
  • Ductal system
  • Secretory alveoli

The authors explicitly acknowledge implications for infection:

“The mammary gland could serve as an alternative replication site for IAV.”

Again: This is what their lab-built H5N1 is capable of.

Federal Funding and Institutional Linkages

The engineered-virus work was funded and executed by:

  • USDA Agricultural Research Service (ARS)
  • National Animal Disease Center (USDA)
  • Iowa State University
  • Virus and Prion Research Unit (USDA)
  • George Mason University

Funding disclosure:

“This work was also supported in part by the USDA ARS (project number 5030-32000-231-000-D).”

Virus engineering, tissue-binding analysis, and outbreak-response authority sit inside the same federal architecture.

National Security Implications

Laboratory-Engineered Mammary Tropism

The ability of an engineered H5N1 construct to bind to human mammary tissue creates direct concerns for:

  • Breast infection
  • Viral shedding into milk
  • Maternal–neonatal exposure
  • Health worker exposure
  • Supply chain vulnerabilities in dairy production

Engineered Cross-Species Compatibility

The synthetic viruses exhibit mammary binding across multiple agricultural species, suggesting the constructs have broad mammalian attachment potential—a trait with dual-use implications.

The Virus’ Characteristics Are Lab-Derived, Not Naturally Observed

Every feature described in the paper—especially mammary binding—is a trait expressed by the engineered constructs they built.

This distinction is essential for policy and oversight.

Bottom Line

This study is not an examination of wild H5N1 behavior.

It is an examination of engineered viral behavior.

The researchers created new chimeric H5N1 viruses using synthetic genetics and a PR8 backbone, and these lab-built constructs showed binding abilities in human breast tissue and the mammary glands of multiple livestock species.

The national-security implications stem directly from these engineered viral traits—not from natural evolution.

Suburban Decay Is Coming To YOUR Town


urban-decay-overgrowth-on-rooftop-rusty

The suburbs, once considered safe havens from urban chaos, are rapidly becoming ground zero for a new wave of danger. The growing presence of violent criminal gangs, many of whom are migrants flooding into the country as part of a government plot to punish suburban communities, is turning these once-peaceful areas into lawless zones. It’s not just anecdotal anymore—it’s happening right in front of our eyes.

One clear example of this suburban decay is the situation at Moreno Valley Mall in California. This mall, like many others across the country, has been overrun by unruly teens causing chaos. And this is not an isolated incident. Malls in places like New Jersey and Pittsburgh are enacting curfews, banning teenagers from being inside after certain hours unless accompanied by an adult, and creating “waiting zones” for teens needing rides after curfew. These measures are a direct response to a spree of looting and violence that began during the so-called “summer of love” in 2020—and has only escalated since.

The result? Shopping malls, once symbols of suburban prosperity, are now unsafe. Stores like CVS and Target are locking up basic goods, and violent confrontations in malls have become a regular occurrence. And this isn’t just a problem in the cities anymore. It’s spreading to the suburbs, where liberal district attorneys refuse to prosecute criminals, emboldening bad actors to strike with little fear of consequences.

The influx of migrants into suburban areas is accelerating this decline. These individuals, often without proper vetting or legal status, are being funneled into these communities, causing a dramatic increase in crime. This isn’t a random consequence—it’s part of a deliberate government plan to punish the suburbs for their political leanings. Many of these areas, traditionally conservative and resistant to progressive policies, are being flooded with people who have no ties to the community and no respect for its laws.

This shift is part of a broader strategy to destabilize the suburbs and break down their resistance to government overreach. The Biden-Harris administration, along with far-left radicals in local governments, seems intent on punishing suburban families by placing violent criminal invaders right on their doorsteps. It’s not enough for them to watch inner cities crumble—they want the same chaos to engulf the suburbs, too.

The lamentations of media personalities like Angela Poe Russell, who mourn the loss of “safe” places for teens to hang out, only underscore how dangerous things have become. Russell reflects nostalgically on the time she spent at malls in her youth—working her first job, meeting her first boyfriend, and making memories. But here’s the cold, hard truth: the key word she uses is “safe.” And malls, like the communities they serve, are no longer safe.

The reality is that the same forces driving up crime in inner cities—government-sanctioned lawlessness, soft-on-crime policies, and unchecked migration—are now infiltrating the suburbs. The same liberal DAs who refuse to prosecute criminals in urban areas are ensuring that the criminals feel emboldened to move into suburban areas, knowing they won’t face serious repercussions there either. And with every new wave of migrants being transported into suburban communities, the threat only grows.

Suburban families must face a hard truth: the government is not interested in protecting them. In fact, they seem intent on putting you in harm’s way. The influx of violent criminals, the collapse of local law enforcement, and the increase in property crimes are not random developments. They are part of a coordinated effort to punish the suburbs for resisting the progressive agenda.

So what can you do? First and foremost, be aware that your community is changing—and not for the better. Prepare your home and your family for the increasing likelihood of violence. Lock your doors, invest in home security, and stay informed about what’s happening in your area. Don’t expect the police or the government to save you. They’ve made it clear that they have other priorities.

The suburbs are no longer a refuge from the dangers of the world. The threat is here, and it’s growing. It’s time to wake up, be vigilant, and understand that the days of peaceful, suburban living are rapidly fading away.

What are you doing to prepare your family for suburban decay?