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CDC Creates New Bird Flu Virus With Enhanced Immune System Evasion in Georgia Lab: Journal ‘npj Viruses’

U.S. gov’t makes pandemic-grade H5N1 avian influenza pathogen invisible to the immune system’s defenses—in just six days.

A new study published last month in npj Viruses describes how the U.S. Centers for Disease Control and Prevention (CDC) engineered a brand-new strain of bird flu in its Atlanta, Georgia laboratories.

The current head of the CDC is Jim O’Neil.

The risky research involved scientists from the CDC in Atlanta, the J. Craig Venter Institute (Rockville, MD, and La Jolla, CA), and the University of California San Diego.

Authors included Li Wang, Masato Hatta, Chenchen Feng, Paul Carney, Benjamin Rambo-Martin, Vivien G. Dugan, C. Todd Davis, James Stevens, Bin Zhou, and others—a team that directly manipulated the H5N1 virus using genetic engineering.

The COVID-19 pandemic was the result of lab-engineered pathogen creation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA—raising grave questions about why U.S. government scientists are once again creating novel, immune-evading strains of dangerous viruses inside federal laboratories.

The new study was published the same month U.S. President Donald Trump stood before the United Nations and called for an end to the creation of biological weapons, even as U.S. government labs like the CDC continue engineering deadly new pathogens under the banner of pandemic preparedness.Subscribe

Why the CDC Says It Built a New Virus

In 2024, a Missouri patient was reported to be infected with an H5N1 virus carrying two unusual mutations in its surface protein (hemagglutinin).

Oddly, the CDC said it was unable to isolate a live virus from the sample.

To study it, the authors said they had to engineer a synthetic version of the Missouri virus by inserting the mutations into the backbone of a cattle-outbreak strain.

The paper itself says:

“Because virus isolation was unsuccessful, the generation of a recombinant virus carrying these substitutions was necessary…”

In other words, the CDC built this new H5N1 in the lab.

The government engineered a man-made disease-causing construct that had never been seen in nature before.

Where the Work Took Place

The study makes clear this was CDC-led work inside federal labs in Georgia:

“All experiments involving highly pathogenic avian influenza (HPAI) A(H5N1) viruses were conducted in Biosafety Level 3 enhanced (BSL-3E) or Animal Biosafety Level 3 (ABSL-3) laboratories at the U.S. Centers for Disease Control and Prevention (CDC), including enhancements required by the U.S. Department of Agriculture and the Federal Select Agent Program.”

This confirms the location (Atlanta, Georgia) and the agency (CDC) responsible.

What the Mutations Did

Two mutations were introduced: P136S and A156T.

The most important one is A156T, which changed how the virus interacts with the immune system.

The study admits:

“The HA P136S/A156T substitutions altered the antigenicity of the 2.3.4.4b A(H5N1) virus, most likely through the introduction of an N-linked glycosylation site at residue 154 enabled by the A156T substitution. This glycosylation likely shields antigenic site B from antibody recognition, resulting in reduced HI and neutralization titers…”

This means the virus was said to have gained a new sugar coating at residue 154, which acted like a shield, hiding it from antibodies that would normally detect it.

Immune Evasion Results

The effect was dramatic and alarming.

Antibodies that normally neutralize H5N1 were far less effective against the engineered virus.

The study shows:

“Introduction of the A156T substitution led to at least a 4-fold reduction in HI titers for all antisera… In the neutralization assay, antisera to TX37 and MI90 showed significantly reduced neutralizing activity against viruses carrying the A156T substitution.”

That means antibodies were four times less effective at minimum, and in some tests, over 99% less effective at neutralizing the new virus.

Put plainly: CDC gave H5N1 a mutation that made it invisible to the immune system’s defenses.

Speed of Engineering

One of the most startling admissions is how quickly the CDC created this recombinant bird flu:

“From the time the partial HA sequence was obtained on September 13, 2024, to the completion of plasmid construction, virus rescue, and the first HI results on September 23, only 10 calendar days (6 business days) had elapsed.”

In other words, within 10 days, the CDC had gone from partial genetic data to a fully functional, lab-built H5N1 virus.

This shows just how rapidly government labs can create new pandemic-grade pathogens.

Bottom Line

The CDC admits in its own paper that it engineered a new strain of H5N1 bird flu in its Georgia labs—a strain that had never existed in nature.

The stated purpose was to study two mutations (P136S and A156T) found in a human patient.

One of those mutations, A156T, created a sugar shield that dramatically reduced antibody recognition, in some cases by more than 99%.

Federal scientists demonstrated, and published, that they can build new, immune-evading strains of one of the world’s deadliest viruses in a matter of days.

That is the very description of gain-of-function experimentation—and it was funded and carried out by the CDC itself.

USDA, NIH, NIAID Fund Creation of Lab-Engineered Bird Flu Viruses With Enhanced Growth and Replication Traits in Nebraska

After Trump calls for ending bioweapons creation.

The U.S. Department of Agriculture (USDA) and the National Institutes of Health (NIH)—specifically its National Institute of Allergy and Infectious Diseases (NIAID)—have funded scientists at the University of Nebraska–Lincoln to create brand-new, never-before-seen influenza viruses through laboratory engineering, according to a September 21 preprint posted on bioRxiv.

The authors claim their aim was vaccine development, but the methods reveal the deliberate construction of novel pathogens with enhanced laboratory growth traits.

The COVID-19 pandemic was the result of lab-engineered pathogen creation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA.

The revelation of this federally funded creation of novel pathogens on American soil comes just days after President Donald Trump stood before the United Nations calling for (here) a global end to bioweapons research, raising profound questions about whether “vaccine development” is now serving as the cover for the very gain-of-function experiments he condemned.

Stated Aim: A New Vaccine for Cattle

The paper frames its purpose around the 2024 detection of H5N1 bird flu in U.S. dairy herds and the lack of licensed cattle vaccines.

The authors present their work as an effort to design a “centralized consensus H5 vaccine” delivered with adenovirus vectors, hoping to elicit both systemic and mucosal immunity in calves.

They argue that such a vaccine would reduce agricultural losses and “remove cattle as a newly established reservoir for zoonotic spread” of bird flu.

Yet beneath the stated goal of protecting cattle lies the undeniable reality that U.S. tax dollars are being used to build entirely new influenza strains in the lab—dangerous, pandemic-causing pathogens created under the banner of “vaccine development.”

What They Actually Did: Built New Viruses That Never Existed in Nature

Instead of working with purportedly circulating H5N1 isolates, the team engineered new pathogens using reverse genetics:

• Six internal gene segments (PB1, PB2, PA, NP, M, and NS) were pulled from the PR8 H1N1 laboratory strain, which is optimized for high replication in mammalian cells and chicken eggs.
• These were combined with synthetic H5 and N genes stripped of their natural multibasic cleavage site.
• The result: novel reassortant influenza viruses with enhanced lab replication efficiency compared to wild-type H5N1.

The viruses were generated in HEK293 and MDCK cells, then amplified in embryonated chicken eggs, all under BSL-2 laboratory conditions at the University of Nebraska–Lincoln.

Enhanced Growth and Replication Traits

By design, the engineered viruses gained new functions not seen in nature:

• Enhanced growth efficiency in eggs and mammalian cells from the PR8 backbone.
• Streamlined replication for lab handling.
• BSL-2 compatibility, expanding the number of facilities able to handle them.

Who Did the Work

• Joshua Wiggins
• Adthakorn Madapong
• Eric A. Weaver (corresponding author).

All three are affiliated with the Nebraska Center for Virology and the School of Biological Sciences at the University of Nebraska–Lincoln.

Where It Was Done

• Genetic engineering, reverse genetics virus creation, and animal studies were all performed at the University of Nebraska–Lincoln, under IBC and IACUC approvals.
• Work was conducted in BSL-2+ labs, required only for moderate-risk agents, despite the fact that the study involved the creation of novel influenza viruses capable of causing pandemics.

Who Paid for It

• USDA National Institute of Food and Agriculture (NIFA), Agriculture and Food Research Initiative (Grant Nos. 2020-06448, 2024-08723).
• NIH – NIAID (Grant No. 1R01AI147109).

Bombshell Details

• Replication-Competent Vectors: The study used replication-competent adenovirus vaccine platforms (Ad28 and Ad48) that can spread within the host, unlike safer replication-deficient types.
• Failed Protection Against the Actual Threat: Despite claims of vaccine promise, the engineered vaccine produced no protective neutralization against the circulating bovine H5N1 strain (Bovine/24)—the virus causing real outbreaks in U.S. cattle.
• No Cattle Challenge Studies: The vaccine was never tested against live infection in cattle, only in mice.
• Sex Bias: Only male calves were tested, ignoring potential sex differences in immune response. By testing only male calves, the study ignored well-established sex differences in immunity—females typically mount stronger antibody and T-cell responses but also suffer higher rates of adverse reactions—leaving half the population unaccounted for and casting doubt on the safety and applicability of the findings.

Bottom Line

While the University of Nebraska team presented their work as vaccine development, the methods show they constructed brand-new bird flu viruses through reverse genetics, engineered with a PR8 laboratory backbone to enhance replication traits.

These pathogens, created with federal funding, were built and amplified under BSL-2 conditions—labs designed for moderate-risk microbes, not novel influenza strains with pandemic potential.

The authors claim their goal was to stop the spread of H5N1 in cattle, but the vaccine failed to neutralize the very strain now circulating in U.S. herds, was never tested in cattle challenges, and excluded females altogether.

Coming just days after President Trump’s UN call to end bioweapons creation, this project exemplifies the dangerous reality that pandemic-capable pathogens are being created under the guise of “vaccine development.”

On American soil.

With American tax dollars.

Sound familiar?

U.S. and South Korean Scientists Lab-Engineer Frankenstein Bird Flu Viruses in Georgia: Journal ‘Virology’

Georgia State University is creating pandemic-capable mutant avian influenza pathogens with NIH funding.

This month, the journal Virology published a study confirming that U.S. researchers at Georgia State University and South Korean collaborators from Jeju National University and Sungshin Women’s University are using reverse genetics to create chimeric H5N1 “Frankenstein” bird flu viruses.

The study was supported by the National Institutes of Health (NIH) and National Institute of Allergy and Infectious Diseases (NIAID) grant AI154656.

Researchers combined purported highly pathogenic avian influenza genes with a laboratory H1N1 backbone.

This is not happening in isolation.

It’s unfolding amid international “pandemic preparedness” efforts, where the creation of dangerous bird flu pathogens goes hand-in-hand with the rollout of vaccines as the supposed solution, which no mainstream or non-mainstream sources are warning about—except this website.

It follows the same playbook as COVID-19, which multiple U.S. agencies have said most likely came from a lab incident.

The new bird flu pathogen creation comes as the United Nations has staged its first-ever global bird flu summit, mobilizing 500 officials and scientists to coordinate “control strategies,” surveillance, and vaccination campaigns—confirming that the very governments engineering these Frankenstein viruses are simultaneously organizing the policies and vaccines that will follow.Subscribe

Building Hybrid Pathogens

The paper openly admits to constructing synthetic flu viruses:

“Reverse genetically engineered reassortant H5N1 influenza viruses were generated using hemagglutinin (HA) and neuraminidase genes derived from either A/Vietnam/1203/2004 (Vietnam rgH5N1) or A/Indonesia/05/2005 (Indonesia rgH5N1), with the remaining seven gene segments derived from A/PR/8/34 (H1N1).”

In plain terms: they spliced bird flu proteins from Asian outbreaks onto a lab H1N1 backbone.

That’s a lab-born hybrid that doesn’t exist in nature.

The very definition of engineered pathogen creation.

Inflammatory Collapse

The experiments revealed catastrophic immune reactions:

“Vaccinated AG129 mice demonstrated significantly higher levels of IL-6, IL-1β, the regulatory cytokine IL-10, and the neutrophil-attracting chemokine KC (CXCL-1) compared to vaccinated A129 mice.”

This translates to runaway lung inflammation—a cytokine storm–like collapse that mirrors the reportedly lethal immune overactivation seen in severe flu and COVID cases.

The Authors

Here are all of the authors, some also holding affiliations in South Korea:

• Ki-Hye Kim
• Hye Suk Hwang
• Youri Lee
• Yu-Jin Jung
• Eun-Ju Ko
• Jae Min Song
• Sang-Moo Kang.

But all of them are affiliated with Georgia State University in Atlanta, which you can contact here.

Bottom Line

The paper proves two damning facts:

1. Engineered bird flu hybrids were built in a U.S. lab with help from South Korea, using reverse genetics.
2. These constructs triggered lethal inflammatory outcomes when combined with vaccination.

This is not preparation, but orchestration.

It’s the same pattern we saw before the COVID-19 pandemic, now being repeated with bird flu.

This isn’t isolated “basic science.”

It’s a pipeline: build dangerous pathogens, then promote vaccines as the “solution.”

The COVID-19 pandemic was said to have been caused by this very thing.

U.N. Stages First-Ever ‘Global Dialogue’ for Bird Flu, Mobilizes 500 International ‘Experts and Decision-Makers’ for Pandemic Coordination

Prioritizing “control strategies” for backyard poultry systems, early warning systems, vaccination strategies, and biosecurity measures.

In another unprecedented instance of worldwide bird flu pandemic coordination, the Food and Agriculture Organization of the United Nations (FAO) has mobilized “around 500 experts and decision-makers to galvanize multisectoral collaboration and investment” at a three-day meeting in Foz do Iguaçu, Brazil.

The FAO’s latest move comes as scientists in Brazil’s Butantan Institute recently engineered never-before-seen H5 bird flu pathogens using reverse genetics—chimeric lab-built viruses that never existed in nature, created under the banner of “pandemic vaccine preparedness.”

Led by Secretary-General António Guterres of Portugal, the United Nations is a highly influential body that can shape international laws, economies, and policies, as many critics view its push for centralized global governance as a dangerous step toward eroding national sovereignty.

The U.N. exploited its unprecedented power during the COVID-19 pandemic by endorsing harsh emergency measures that led to widespread human rights abuses, including repression, censorship, and excessive force against vulnerable populations under the guise of crisis control.

As this website has exclusively been reporting, Brazil, the United States, Japan, South Korea, Egypt, and several countries in Europe are all coordinating bird flu gain-of-function research, reverse-genetics experiments, and vaccine development.

Together, these developments show a coordinated global apparatus in which the same governments engineering new bird flu pathogens are simultaneously assembling under the U.N. to dictate the vaccines and policies that will follow.

Unprecedented International Bird Flu Mobilization

For the first time in history, the United Nations has staged a worldwide bird flu summit, bringing together hundreds of handpicked government officials, scientists, corporate executives, and bureaucrats in one room to coordinate pandemic policy.

Just like they did before the COVID-19 outbreak with the infamous “Event 201” exercise, conducted by the Johns Hopkins Center for Health Security in partnership with the World Economic Forum and the Bill and Melinda Gates Foundation.

This is unprecedented.

The U.N. has never before convened this level of global multisectoral coordination on avian influenza.

But it confirms my warning that governments and global institutions aren’t just preparing for pandemics—they’re actively building the infrastructure for them.

While the U.S. is telling the public that it’s about “protecting food security” and “backyard poultry systems,” the deeper reality is clear: the very same governments funding bird flu gain-of-function, reverse genetics, and Frankenstein chimera experiments are now organizing the response framework—and pre-positioning vaccines as the solution.

‘Surveillance, Biosecurity, and Vaccination’

This is pandemic planning.

Beth Bechdol, FAO Deputy Director-General, declared: “Failure is not an option.”

What she did not say is that many of the “solutions” already on the table are vaccine campaigns waiting to be rolled out, designed in lockstep with the engineered crisis itself.

The official agenda is revealing:

• Targeting backyard poultry systems in low-income countries
• Building global early warning systems for outbreak detection
• Expanding vaccination strategies as central to control
• Hardening biosecurity measures across poultry operations
• Integrating animal and human health policy under the U.N.’s “One Health” framework
• Locking in surveillance tools for rapid outbreak response.

Brazil’s Agriculture Minister Carlos Favaro praised his country’s “swift and effective response” to bird flu detection earlier this year, framing it as proof of a “credible sanitary system.”

FAO’s Chief Veterinarian Thanawat Tiensin doubled down on the vaccine-surveillance model, saying: “Improved surveillance, biosecurity, and vaccination when appropriate… are keys to controlling this disease.”

Bottom Line

This was not just another conference.

The U.N. has openly staged a first-of-its-kind global command center for bird flu, aligning governments, corporations, and scientists under one pandemic framework.

While labs around the world continue to manufacture the threat through reckless genetic engineering, the U.N. is setting the stage for mass-coordinated countermeasures—vaccines and surveillance systems—before the next intentional or accidental outbreak even begins.