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NIAID, DARPA, Bill Gates Intentionally Infect 80 Americans With Lab-Made Pandemic Influenza Virus: HHS Study

Majority of infected individuals became contagious to others, raising national security and informed consent concerns.

A federally run experiment funded by the National Institute of Allergy and Infectious Diseases (NIAID), the Defense Advanced Research Projects Agency (DARPA), and the Bill & Melinda Gates Foundation deliberately infected 80 American adults with a lab-grown pandemic influenza virus at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

Data from 74 of those infected were analyzed, and 53 of them (72% of analyzed participants, or at least 66% of all infected participants) were confirmed to be shedding the pathogen, meaning they were actively contagious and could infect others.

We do not know whether six participants who were excluded from the study after being deliberately infected were shedding the virus or not.

Regardless, 53 of the individuals became contagious to others.

The human-infection experiment—officially published in Science Translational Medicine (Aug. 2025) under the title “Nasal and systemic immune responses correlate with viral shedding after influenza challenge in people with complex preexisting immunity”—was conducted entirely under the jurisdiction of the U.S. Department of Health and Human Services (HHS).

The original HHS manuscript can be found here or downloaded below.

Nihms 2097372 (2)

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Lab-Made Pandemic Virus Used to Infect Humans

According to the paper, participants were “challenged with 10⁷ half-maximal tissue culture infectious dose (TCID₅₀) of a 2009 pandemic H1N1 strain, A/Bethesda/MM2/H1N1.”

That purported virus was not naturally circulating.

It was a lab-engineered clone of the 2009 pandemic influenza A (H1N1) virus, manufactured by NIH scientists in Bethesda and maintained as a standardized “human challenge” stock.

The virus name itself—A/Bethesda/MM2/H1N1—identifies it as an NIH-made strain.

The “Bethesda” designation marks its laboratory origin at NIH’s Maryland facility, and “MM2” denotes the second master-mix batch of the cloned challenge stock.

80 Individuals Deliberately Infected Under HHS Oversight

The study describes the deliberate exposure of 80 adults to this laboratory-made pandemic influenza strain in 2019.

“The challenge study (clinicaltrials.gov NCT01971255) was performed at the NIH Clinical Center between April and October 2019,” the study reads.

Interestingly, that means the 80 human participants were intentionally infected with the NIH-made H1N1 influenza virus roughly five to six months before COVID-19 was first reported in Wuhan, China (December 2019).

So, while the study was published in Science Translational Medicine in August 2025, the actual human infections occurred in mid-2019.

Half of those deliberately infected had been vaccinated roughly two months earlier with a commercial quadrivalent influenza vaccine; the other half had not.

“All 80 participants were brought into the NIH Clinical Center as mixed cohorts and challenged with 10⁷ TCID₅₀ of influenza A/Bethesda/MM2/H1N1 virus … and assessed daily for a minimum of 9 days.”

Although only 74 participants were ultimately included in the analysis (after six were excluded), every one of them was intentionally inoculated with a live, replication-competent pandemic virus.

The experiment was run on U.S. federal property by U.S. government scientists.

It was approved by the NIAID Institutional Review Board (IRB No. 19-I-0058), making it an officially sanctioned HHS human-infection study.

The human infection experiment was carried out under a multi-million U.S. taxpayer dollar project titled “Universal Influenza Vaccine Development” (project number 1ZIAAI001372), led by Dr. Jeffery Taubenberger.

Dr. Taubenberger—listed as an author on the study—is the current NIAID Director, taking over Anthony Fauci’s spot.

Taubenberger holds a patent for the carcinogenic BPL technology at the center of the Trump administration’s new ‘Generation Gold Standard’ influenza bird flu pandemic vaccine platform.

His agency is also directing U.S. tax dollars to fund the creation of never-before-seen “Frankenstein” bird flu viruses.

Confirmed 72% of Analyzed Participants—& at Least 66% of All Infected—Became Infectious

A total of 80 volunteers were deliberately infected with the NIH-made influenza virus, but data from only 74 participants were included in the final published analysis.

Among those 74 analyzed participants, 53 were confirmed to actively shed virus, meaning they were contagious.

Because the six excluded individuals were not evaluated for viral shedding, the true number of infectious participants could be higher, but only 53 are confirmed in the published dataset.

That equates to 72% of the analyzed group and at least 66% of everyone infected becoming contagious, some for several days.

Shedding was tracked by daily nasal swabs using the BioFire Respiratory Pathogen Panel and qRT-PCR testing for the influenza M gene.

Participants were considered “shedding” when viral RNA was detected in nasal-wash samples.

“[P]articipants shedding virus for two or more days showed higher early viral loads and exhibited stronger induction of antiviral responses compared with participants who shed virus for one day.”

The highest viral loads appeared in multiday shedders on days 1–3 post-infection, coinciding with the most severe flu-like symptoms, as measured by NIH’s FluPro symptom scoring system.

Vaccination Failed to Prevent Infection or Shedding

Vaccination did not prevent infection.

The paper admits that “vaccinated shedders” displayed increased T-cell activity and inflammatory markers, including CD8A, PD-L1, IFN-γ, IL-6, and TNF-β, compared to unvaccinated shedders—indicating that vaccination did not stop infection but instead triggered a hyper-inflammatory immune response.

Females were three times more likely to clear the infection after only one day of shedding, while males were more likely to shed virus for multiple days.

Funding: NIAID, DARPA, and Gates Foundation

The study lists its financial backers as:

• NIAID Intramural Research Program (grants AI000986-12 and AI001157-07)
• DARPA (Defense Advanced Research Projects Agency), contract HR0011831160
• Bill & Melinda Gates Foundation, grant OPP1178956

That combination of government and private funders represents the same triad—HHS, the Pentagon, and the Gates Foundation—responsible for many dual-use biological and “pandemic preparedness” programs that blur the line between public health and bio-defense research.

Containment & Biosafety Measures Not Disclosed

Remarkably, the 2025 Science Translational Medicine paper and HHS manuscript provide no description whatsoever of biosafety precautions—no mention of negative-pressure rooms, isolation conditions, or post-infection quarantine protocols to prevent secondary transmission.

Readers of the study are unable to verify how the government prevented infected subjects from spreading the lab-made virus to others, raising national security concerns.

It further raises grave informed-consent concerns, as individuals who interacted with these infected volunteers beyond the study setting were never informed that they might be exposed to an NIH-made pandemic influenza virus.

Given that 72 percent of participants were confirmed viral shedders, this omission raises serious biosafety and public-transmission concerns.

Conducted Entirely Under HHS Authority

The trial was hosted, funded, staffed, and overseen by HHS agencies from start to finish:

• Conducted at the NIH Clinical Center in Bethesda, Maryland
• Run by the NIAID Laboratory of Infectious Diseases
• Reviewed by an HHS Institutional Review Board
• Carried out under HHS Good Clinical Practice guidelines

In short, the U.S. Department of Health and Human Services infected 74 American adults with a lab-grown pandemic influenza virus to study viral shedding and immune-system responses—while omitting basic transparency about containment.

The nation’s top health agency is infecting Americans with pandemic-grade pathogens.

Bottom Line

The federally directed experiment—funded by NIAID, DARPA, and the Bill & Melinda Gates Foundation—was a live human-infection challenge using a lab-engineered influenza strain created by NIH scientists in Bethesda.

Eighty adults were deliberately infected with the laboratory-made pandemic H1N1 virus; data from 74 were analyzed, and 53 of them (72 % of those analyzed, or at least 66 % of everyone infected) were confirmed to be shedding the pathogen—actively contagious and capable of transmitting it to others.

The six excluded participants were also infected, but the government provided no data indicating whether they shed virus, leaving the full extent of contagiousness unknown.

No description was provided for biosafety controls, isolation conditions, or post-infection release criteria, meaning the public record offers no verification of how HHS prevented the spread of its own lab-created virus beyond the NIH facility.

This omission raises not only national-security concerns but also informed-consent violations, since people who may have interacted with participants outside the study were never notified of possible exposure to an NIH-made pathogen.

Although the paper frames the experiment as advancing “next-generation vaccine development,” its findings instead showed that vaccination failed to prevent infection or viral shedding and appeared to trigger immune hyperactivation in vaccinated participants.

The newly published HHS study therefore stands as a rare, fully documented example of the U.S. Department of Health and Human Services deliberately infecting American citizens with a laboratory-grown pandemic-grade virus—underwritten by HHS, DARPA, and the Gates Foundation, with no transparent account of how the resulting contagion was contained.

Enough is enough with this shit already.

U.K.-China Gain-of-Function Creates Airborne Bird Flu Viruses Capable of Infecting Humans and Other Mammals: ‘Journal of Virology’

National security in jeopardy as government-funded Chinese–U.K. team engineered bird flu viruses with a new mutation that let them infect human cells and spread through the air between mammals.

A September publication in the Journal of Virology confirms that Chinese and U.K. researchers have jointly created, enhanced, and tested new avian influenza “bird flu” viruses in the lab that acquired the ability to infect and spread among mammals through the air.

Congress, the White House, the Department of Energy, the FBI, and the CIA have confirmed that the COVID-19 pandemic was likely the result of lab-engineered pathogen manipulation.

Such experimentation raises national security and biosafety concerns.

Countries all over the world are performing risky experiments on bird flu viruses while developing drugs for the disease, simultaneously creating both the problem and the solution, raising questions about conflicts of interest and motives.

The new study—led by Dr. Juan Pu and Dr. Jinhua Liu of China Agricultural University—used a plasmid-based reverse-genetics system to construct synthetic viruses based on H9N2, H7N9, and H3N8 avian-influenza backbones.

The team intentionally introduced a new mutation called PB2-E627V, a single amino acid change that does not occur naturally in these strains, which allows bird flu viruses to cross into humans.

“Recombinant viruses were generated using a plasmid-based reverse genetics system in the genetic background of 17/H9N2, 17/H7N9, and 22/H3N8,” the authors wrote.

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What the Mutation Did

The PB2-627V mutation bridged the species barrier between birds and humans by allowing the virus to exploit host proteins in both.

“PB2-627V combines the viral properties of avian-like PB2-627E and human-like PB2-627K, facilitating AIVs to efficiently infect and replicate in chickens and mice by utilizing both avian- and human-origin ANP32A proteins.”

In other words, the modified viruses replicated like avian strains in birds and like human flu viruses in mammals—a dual-host adaptation that overcomes the natural molecular restriction that normally prevents bird flu from establishing infection in humans.

Aerosol Transmission in Mammals

Perhaps most disturbing, the researchers infected ferrets—the most widely accepted mammalian model for human influenza—and documented respiratory-droplet (aerosol) transmission.

“PB2-627V promotes efficient transmission between ferrets through respiratory droplets.”

This means the engineered H9N2 strain became airborne and contagious between mammals, an outcome that squarely fits the U.S. government’s definition of “enhanced Potential Pandemic Pathogen” (ePPP) research under the HHS P3CO framework, which covers any experiment that enhances the transmissibility or virulence of a pathogen so that it is likely capable of widespread and uncontrollable transmission in human populations.

Replication in Chickens, Mice, & Humans

The study showed that the lab-created viruses replicated efficiently in chicken lungs, increased viral loads in human-cell cultures, and caused more severe pathology in mice than wild-type strains.

The viruses were also serially passaged through five generations of live chickens, proving that PB2-627V remains genetically stable and transmissible in poultr.

This means the mutation could sustain itself in farm flocks and later spill over to people.

“PB2-627V showed a high potential for sustained prevalence in chickens,” the authors concluded.

Funded by Chinese & British Governments

The paper lists funding only from China and the United Kingdom:

“This work was funded by the National Key Research and Development Program of China (2021YFD1800202 and 2022YFF0802400 [J.P.] and 2024YFE0106000 [J.L.]), National Natural Science Foundation of China (32192450 [J.L.] and 32102661 [Z.J.]), and UK Biotechnology and Biological Sciences Research Council BBS/E/D/20002173 and UK Medical Research Council MR/Y015045/1”

Collaborating institutions included the Roslin Institute (University of Edinburgh), the University of Nottingham, and the University of Hong Kong, alongside China Agricultural University in Beijing.

In plain terms: the Chinese and British governments jointly funded and executed gain-of-function experiments that engineered avian flu viruses to infect mammals through the air.

Biosecurity & Ethical Concerns

The authors admit that contamination occurred in sequencing samples, though they claim those data were “excluded from the final results.”

“Due to potential contamination identified in sequencing samples from the second and third parallel experiments during subsequent analysis, all data from these experiments were excluded from the final results,” the study reads.

That means while performing next-generation sequencing (NGS) on viral samples, the researchers detected contamination in some of their experimental batches—specifically, in the second and third parallel experiments.

Such an admission in a study manipulating airborne bird flu viruses underlines serious biosafety questions about laboratory conditions and oversight.

There is no mention of independent biosecurity review, P3CO-style oversight, or international ethics board approval for the gain-of-function component of the work.

International Risk

The paper acknowledges that the PB2-627V mutation is already spreading naturally across multiple subtypes—including H5N1, H5N6, H7N9, H3N8, and H10N3—and has been found in humans, foxes, minks, tigers, and wild birds.

The authors warn:

“Given the global prominence of AIVs, it will be prudent to monitor influenza viruses for the PB2-627V mutation as a potential marker for zoonotic spread.”

That is an understatement.

What they have demonstrated is that lab-modified avian-flu viruses can now infect mammals and transmit through the air—a benchmark for pandemic-capable pathogens.

Bottom Line

The Journal of Virology paper by Guo et al. (2025) provides direct evidence that:

• China and the United Kingdom jointly conducted gain-of-function experiments on avian flu viruses.
• The resulting strains crossed the species barrier and became airborne between mammals.
• These experiments meet the U.S. government’s definition of enhanced Potential Pandemic Pathogen (ePPP) research.

In short: Western and Chinese scientists have again created lab-made bird-flu viruses capable of infecting mammals through the air—exactly the kind of experiment international biosecurity laws were supposed to prevent.

NIAID, DARPA, Bill Gates Intentionally Infect 80 Americans With Lab-Made Pandemic Influenza Virus: HHS Study

Majority of infected individuals became contagious to others, raising national security and informed consent concerns.

A federally run experiment funded by the National Institute of Allergy and Infectious Diseases (NIAID), the Defense Advanced Research Projects Agency (DARPA), and the Bill & Melinda Gates Foundation deliberately infected 80 American adults with a lab-grown pandemic influenza virus at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

Data from 74 of those infected were analyzed, and 53 of them (72% of analyzed participants, or at least 66% of all infected participants) were confirmed to be shedding the pathogen, meaning they were actively contagious and could infect others.

We do not know whether six participants who were excluded from the study after being deliberately infected were shedding the virus or not.

Regardless, 53 of the individuals became contagious to others.

The human-infection experiment—officially published in Science Translational Medicine (Aug. 2025) under the title “Nasal and systemic immune responses correlate with viral shedding after influenza challenge in people with complex preexisting immunity”—was conducted entirely under the jurisdiction of the U.S. Department of Health and Human Services (HHS).

The original HHS manuscript can be found here or downloaded below.

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Lab-Made Pandemic Virus Used to Infect Humans

According to the paper, participants were “challenged with 10⁷ half-maximal tissue culture infectious dose (TCID₅₀) of a 2009 pandemic H1N1 strain, A/Bethesda/MM2/H1N1.”

That purported virus was not naturally circulating.

It was a lab-engineered clone of the 2009 pandemic influenza A (H1N1) virus, manufactured by NIH scientists in Bethesda and maintained as a standardized “human challenge” stock.

The virus name itself—A/Bethesda/MM2/H1N1—identifies it as an NIH-made strain.

The “Bethesda” designation marks its laboratory origin at NIH’s Maryland facility, and “MM2” denotes the second master-mix batch of the cloned challenge stock.

80 Individuals Deliberately Infected Under HHS Oversight

The study describes the deliberate exposure of 80 adults to this laboratory-made pandemic influenza strain in 2019.

“The challenge study (clinicaltrials.gov NCT01971255) was performed at the NIH Clinical Center between April and October 2019,” the study reads.

Interestingly, that means the 80 human participants were intentionally infected with the NIH-made H1N1 influenza virus roughly five to six months before COVID-19 was first reported in Wuhan, China (December 2019).

So, while the study was published in Science Translational Medicine in August 2025, the actual human infections occurred in mid-2019.

Half of those deliberately infected had been vaccinated roughly two months earlier with a commercial quadrivalent influenza vaccine; the other half had not.

“All 80 participants were brought into the NIH Clinical Center as mixed cohorts and challenged with 10⁷ TCID₅₀ of influenza A/Bethesda/MM2/H1N1 virus … and assessed daily for a minimum of 9 days.”

Although only 74 participants were ultimately included in the analysis (after six were excluded), every one of them was intentionally inoculated with a live, replication-competent pandemic virus.

The experiment was run on U.S. federal property by U.S. government scientists.

It was approved by the NIAID Institutional Review Board (IRB No. 19-I-0058), making it an officially sanctioned HHS human-infection study.

The human infection experiment was carried out under a multi-million U.S. taxpayer dollar project titled “Universal Influenza Vaccine Development” (project number 1ZIAAI001372), led by Dr. Jeffery Taubenberger.

Dr. Taubenberger—listed as an author on the study—is the current NIAID Director, taking over Anthony Fauci’s spot.

Taubenberger holds a patent for the carcinogenic BPL technology at the center of the Trump administration’s new ‘Generation Gold Standard’ influenza bird flu pandemic vaccine platform.

His agency is also directing U.S. tax dollars to fund the creation of never-before-seen “Frankenstein” bird flu viruses.

Confirmed 72% of Analyzed Participants—& at Least 66% of All Infected—Became Infectious

A total of 80 volunteers were deliberately infected with the NIH-made influenza virus, but data from only 74 participants were included in the final published analysis.

Among those 74 analyzed participants, 53 were confirmed to actively shed virus, meaning they were contagious.

Because the six excluded individuals were not evaluated for viral shedding, the true number of infectious participants could be higher, but only 53 are confirmed in the published dataset.

That equates to 72% of the analyzed group and at least 66% of everyone infected becoming contagious, some for several days.

Shedding was tracked by daily nasal swabs using the BioFire Respiratory Pathogen Panel and qRT-PCR testing for the influenza M gene.

Participants were considered “shedding” when viral RNA was detected in nasal-wash samples.

“[P]articipants shedding virus for two or more days showed higher early viral loads and exhibited stronger induction of antiviral responses compared with participants who shed virus for one day.”

The highest viral loads appeared in multiday shedders on days 1–3 post-infection, coinciding with the most severe flu-like symptoms, as measured by NIH’s FluPro symptom scoring system.

Vaccination Failed to Prevent Infection or Shedding

Vaccination did not prevent infection.

The paper admits that “vaccinated shedders” displayed increased T-cell activity and inflammatory markers, including CD8A, PD-L1, IFN-γ, IL-6, and TNF-β, compared to unvaccinated shedders—indicating that vaccination did not stop infection but instead triggered a hyper-inflammatory immune response.

Females were three times more likely to clear the infection after only one day of shedding, while males were more likely to shed virus for multiple days.

Funding: NIAID, DARPA, and Gates Foundation

The study lists its financial backers as:

• NIAID Intramural Research Program (grants AI000986-12 and AI001157-07)
• DARPA (Defense Advanced Research Projects Agency), contract HR0011831160
• Bill & Melinda Gates Foundation, grant OPP1178956

That combination of government and private funders represents the same triad—HHS, the Pentagon, and the Gates Foundation—responsible for many dual-use biological and “pandemic preparedness” programs that blur the line between public health and bio-defense research.

Containment & Biosafety Measures Not Disclosed

Remarkably, the 2025 Science Translational Medicine paper and HHS manuscript provide no description whatsoever of biosafety precautions—no mention of negative-pressure rooms, isolation conditions, or post-infection quarantine protocols to prevent secondary transmission.

Readers of the study are unable to verify how the government prevented infected subjects from spreading the lab-made virus to others, raising national security concerns.

It further raises grave informed-consent concerns, as individuals who interacted with these infected volunteers beyond the study setting were never informed that they might be exposed to an NIH-made pandemic influenza virus.

Given that 72 percent of participants were confirmed viral shedders, this omission raises serious biosafety and public-transmission concerns.

Conducted Entirely Under HHS Authority

The trial was hosted, funded, staffed, and overseen by HHS agencies from start to finish:

• Conducted at the NIH Clinical Center in Bethesda, Maryland
• Run by the NIAID Laboratory of Infectious Diseases
• Reviewed by an HHS Institutional Review Board
• Carried out under HHS Good Clinical Practice guidelines

In short, the U.S. Department of Health and Human Services infected 74 American adults with a lab-grown pandemic influenza virus to study viral shedding and immune-system responses—while omitting basic transparency about containment.

The nation’s top health agency is infecting Americans with pandemic-grade pathogens.

Bottom Line

The federally directed experiment—funded by NIAID, DARPA, and the Bill & Melinda Gates Foundation—was a live human-infection challenge using a lab-engineered influenza strain created by NIH scientists in Bethesda.

Eighty adults were deliberately infected with the laboratory-made pandemic H1N1 virus; data from 74 were analyzed, and 53 of them (72 % of those analyzed, or at least 66 % of everyone infected) were confirmed to be shedding the pathogen—actively contagious and capable of transmitting it to others.

The six excluded participants were also infected, but the government provided no data indicating whether they shed virus, leaving the full extent of contagiousness unknown.

No description was provided for biosafety controls, isolation conditions, or post-infection release criteria, meaning the public record offers no verification of how HHS prevented the spread of its own lab-created virus beyond the NIH facility.

This omission raises not only national-security concerns but also informed-consent violations, since people who may have interacted with participants outside the study were never notified of possible exposure to an NIH-made pathogen.

Although the paper frames the experiment as advancing “next-generation vaccine development,” its findings instead showed that vaccination failed to prevent infection or viral shedding and appeared to trigger immune hyperactivation in vaccinated participants.

The newly published HHS study therefore stands as a rare, fully documented example of the U.S. Department of Health and Human Services deliberately infecting American citizens with a laboratory-grown pandemic-grade virus—underwritten by HHS, DARPA, and the Gates Foundation, with no transparent account of how the resulting contagion was contained.

NIAID Director Holds Patent for Bird Flu Pandemic Vaccine—as His Agency Creates Frankenstein Bird Flu Viruses in the Lab

Dr. Jeffery Taubenberger is creating the pandemic pathogen problem and the royalty-collecting vaccine solution at the same time—raising lab leak, national security, and conflict of interest concerns.

The U.S. National Institute of Allergy and Infectious Diseases (NIAID) is funding the laboratory creation of deadly, genetically engineered bird-flu viruses—even as its director, Dr. Jeffery Taubenberger, is named as an inventor on a U.S. government patent for a vaccine platform designed to counter those very pathogens.

In other words, the same federal agency making new bird-flu viruses is led by the man who helped invent—and could profit from—the vaccine meant to fight them.

Mainstream reports and federal documents confirm that Dr. Taubenberger could receive royalty payments if the vaccine platform proves successful.

Federal rules allow government inventors like Taubenberger to personally earn up to $150,000 a year in royalties from their patents.

This overlap between virus creation and vaccine ownership raises profound questions about conflicts of interest within America’s pandemic-preparedness system.

The same official overseeing the creation of potentially pandemic-causing bird-flu viruses also stands to earn personal income from the patented vaccine technology designed to combat them—a built-in conflict of interest at the very heart of U.S. pandemic research.

How secure is a nation whose top infectious-disease officials are simultaneously funding the creation of potential pandemic pathogens and positioned to profit from the vaccines meant to stop them?

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Who Is Jeffery Taubenberger?

NIAID Director Dr. Jeffery Taubenberger gained fame for leading the team that sequenced and reconstructed the 1918 “Spanish flu” genome—the deadliest pandemic in modern history.

Dr. Taubenberger’s work on the Spanish flu virus involved the reconstruction and sequencing of one of the deadliest pandemics in history.

That project effectively resurrected an extinct virus under federal sponsorship, establishing Taubenberger as a pioneer of gain-of-function influenza research.

Bird flu belongs to the influenza family, meaning the very expertise Taubenberger developed by resurrecting the 1918 virus now underpins his agency’s funding of new, lab-engineered avian-influenza strains with similarly pandemic-capable properties.

Taubenberger replaced Anthony Fauci as acting NIAID director on April 25, 2025, following Fauci’s retirement in December 2022 and Jeanne Marrazzo’s tenure as director from 2023 until 2025.

Like Fauci before him, Taubenberger now presides over an agency channeling taxpayer dollars into the same kind of high-risk pathogen manipulation that helped set the stage for the COVID-19 disaster—continuing the very pattern of federally backed experimentation that muddles public health preparedness and pandemic provocation.

Bird Flu Takes Center Stage in Trump’s $500 Million ‘Generation Gold Standard’ Project

Under President Donald J. Trump, HHS and the NIH in May 2025 launched ‘Generation Gold Standard,’ a $500 million “next-generation, universal vaccine platform” centered on avian-influenza (“bird flu”) jab creation.

“These vaccines aim to provide broad-spectrum protection against multiple strains of pandemic-prone viruses like H5N1 avian influenza and coronaviruses including SARS-CoV-2, SARS-CoV-1, and MERS-CoV,” an HHS press release states.

The lead candidates—BPL-1357 and BPL-24910—use beta-propiolactone (BPL)-inactivated, whole-virus platforms.

Clinical trials are scheduled for 2026, with FDA review targeted for 2029.

The Patent & Potential Financial Stakes

Dr. Taubenberger is a named inventor on the BPL-inactivated bird-flu vaccine patent developed within NIH laboratories.

That means he holds a patent for the bird-flu vaccines at the center of Trump’s Generation Gold Standard program.

A May 2025 report in Science confirms that NIH “has two patents for the BPL-inactivated, universal flu vaccine,” that Taubenberger “is named as one of the inventors,” and that the NIAID director “stands to financially benefit from this project.”

The patent is confirmed in a Federal Register notice from December 2019.

The relevant patent application is titled “Broadly Protective Influenza Vaccine Comprising a Cocktail of Inactivated Avian Influenza Viruses.”

Put plainly, the federal official directing America’s bird-flu virus research is also positioned to earn personal royalties from the very vaccine platform his own agency is funding—tying Taubenberger’s financial interests directly to the emergence of a bird flu pandemic.

The Dual-Track Pattern Echoes of COVID-19

This dual track—create the pathogen, then sell the cure—echoes the pattern seen before COVID-19, when EcoHealth Alliance’s DEFUSE project proposed engineering chimeric coronavirus spikes and aerosolized self-spreading vaccines years before the 2019 outbreak.

A Frontiers in Virology study confirmed that Moderna’s 2016 patented spike-protein sequence—developed in partnership with DARPA years before the COVID-19 outbreak—matched the pandemic virus’s spike sequence with a one-in-three-trillion probability of occurring naturally.

Later, congressional investigators discovered that DARPA, the Department of Defense, and the Office of the Director of National Intelligence had classified and concealed EcoHealth Alliance’s DEFUSE proposal.

The plan outlined how to engineer SARS-like viruses with furin cleavage sites.

It prompted Senator Roger Marshall to warn that the cover-up may “rise to the level of misconduct, false statements, obstruction of federal proceedings, conspiracy, conflicts of interest, or infractions of administrative or civil laws.”

The parallels are striking: classified projects, overlapping incentives, and opaque oversight.

The New Bird-Flu Playbook

The COVID-19 pandemic was likely the result of lab-engineered pathogen manipulation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA.

Today, U.S. and international laboratories—funded by NIAID—are constructing new bird flu strains using reverse genetics and chimeric-virus methods.

• One recent NIAID-funded project produced a live hybrid H5N1 “Frankenstein” virus that infects human lung cells, resists flu medication, and mutates to evade vaccines.
• In another NIAID-backed project, researchers built entirely new bird-flu viruses with enhanced growth and replication traits.
• At the University of Pittsburgh, NIAID bankrolled experiments that created a never-before-seen chimeric bird-flu virus by fusing H5N1 genes onto a live vesicular stomatitis virus backbone.
• At Georgia State University, U.S. and South Korean researchers—backed by NIAID funding—recently created chimeric H5N1 bird-flu viruses by splicing genes from Asian outbreak strains onto a lab H1N1 backbone, producing synthetic hybrids that triggered severe inflammatory reactions in animal tests.
• At the University of Tokyo and the University of Wisconsin, NIAID-funded researchers led by Yoshihiro Kawaoka rebuilt a pandemic-capable H5N1 virus from synthetic gene clones, deliberately driving mammalian adaptation and drug resistance.
• In another recent NIAID-backed collaboration spanning the U.S., Japan, Egypt, and Austria, scientists used reverse genetics to stitch together wild H5N1 genes with a 1934 lab flu strain—creating a chimeric hybrid virus that proved 100% lethal in mammals.
• At the University of Missouri, NIAID-funded researchers engineered bat–human hybrid influenza viruses through reverse genetics that replicate efficiently in mammalian cells and resist common antivirals.
• In yet another recent NIAID-funded experiment, scientists engineered a multi-strain bird-flu virus in German labs using synthetic plasmids before shipping it to Alabama, where live ferret infection tests with H5N1 were performed under U.S. government direction.

The same tools central to the COVID-19 gain-of-function controversy are again in play.

The outcome is a closed loop: government-funded pathogen creation feeding government-funded vaccine development, overseen by officials with patent ties to the product side.

Bottom Line

Dr. Jeffery Taubenberger—the scientist who resurrected the 1918 flu—now directs NIAID, funds gain-of-function-style bird-flu research, and is a named inventor on the federally patented BPL vaccine platform at the heart of Trump’s $500 million Generation Gold Standard program.

According to Science and federal records, Taubenberger could personally earn royalties—up to $150,000 a year—from the same vaccine platform his own agency is financing, meaning the official funding bird-flu virus creation is also positioned to profit from the “solution.”

That built-in financial stake transforms what should be a public-health mission into a structural conflict of interest—one that blurs the line between national bio-defense and bio-commerce.

Once again, the U.S. government’s pandemic apparatus merges research, regulation, and remuneration—raising the question not of whether the next outbreak is being planned for, but whether it’s being prepared for profit.

NIH Funds Creation of New Frankenstein Bird Flu Virus in Europe—Tests It in Alabama: Journal ‘Vaccine’

Engineered in German labs using reverse genetics, then tested in U.S. animals with live H5N1 challenge.

A peer-reviewed study published this month in Vaccine details how the U.S. National Institutes of Health (NIH)—through its National Institute of Allergy and Infectious Diseases (NIAID)—funded and conducted live H5N1 “bird flu” experiments on ferrets using newly engineered chimeric influenza viruses that were synthetically constructed in Europe from the combined genetic material of multiple flu strains.

NIAID is led by Dr. Jeffery Taubenberger, widely recognized for leading the team that sequenced the 1918 influenza “Spanish flu” pandemic virus genome.

Dr. Taubenberger’s work on the Spanish flu virus involved the reconstruction and sequencing of one of the deadliest pandemics in history.

The revelation of new bird flu pathogen creation follows this website’s report that the NIH, led by Director Jayanta “Jay” Bhattacharya, and USDA have funded scientists to create other brand-new, never-before-seen avian influenza viruses with enhanced growth and replication traits at the University of Nebraska–Lincoln.

The Centers for Disease Control and Prevention (CDC) also recently engineered a brand-new strain of bird flu in its Atlanta, Georgia laboratories, signifying broad, multi-agency coordination of federally backed programs to genetically bioengineer new avian-influenza viruses across multiple institutions.

Moreover, the Department of Health and Human Services’ (HHS) Biomedical Advanced Research and Development Authority (BARDA) recently awarded Cidara $339 million for its new influenza drug CD388.

Each U.S. agency is contributing to a rapidly expanding network of synthetic bird-flu drug development and virus creation with heightened replication efficiency, immune-evasion features, and potential dual-use biosecurity risks.

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Who Funded It

According to the acknowledgments:

“The ferret experiment was funded and carried out by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (USA) non-clinical and preclinical service programs through Southern Research Institute (USA) contract HHSN272201700029I/75N93020F00002 with Treamid Therapeutics GmbH (D.Pleimers).”

The work was supported by Treamid Therapeutics and UniFluVec.

That means the U.S. government financed part of the research, while two private European biotechnology firms oversaw the development of the new virus, signalling international bird flu pandemic orchestration.

The Southern Research Institute in Birmingham, Alabama carried out the ferret infection and live-virus challenge under NIH/NIAID direction.

“The experiment in ferrets was performed by National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Health (USA) and Southern Research Institute (USA),” the study reads.

Where the Viruses Were Created

The paper confirms the engineered viruses were constructed in Europe:

“The recombinant influenza virus vector, UniFluVec, is based on the PR/8/34 influenza virus and constructed using the reverse genetics method with synthetic plasmids generated by GeneArt (Germany).”

That means synthetic plasmids were built by GeneArt, a Thermo Fisher Scientific division in Germany, then used by UniFluVec and Treamid Therapeutics to assemble a brand-new influenza virus before transferring materials for NIH-funded animal testing in the U.S.

What They Created

The new construct, called UniFluVec, is a hybrid influenza virus assembled from several different strains through reverse genetics, a process that reconstructs live viruses from cloned DNA:

“The recombinant influenza virus vector, UniFluVec… constructed using the reverse genetics method… The HA and NA fragments originate from A/Mississippi/10/2013 (H1N1pdm), while PB2, PB1, PA, NP, M and NS fragments—from PR/8/34 (H1N1).”

The authors then spliced in additional genetic material from multiple lineages:

“UniFluVec includes two key modifications in the NS segment: a truncated NS1 protein of 124 amino acids and a heterologous NEP protein from the A/Singapore/1/57-like (H2N2) virus. Additionally, the truncated NS1₁₂₄ protein was fused with a 21-amino-acids of the fusion peptide from the HA2 subunit of the B/Lee/1940 virus and a conserved nine-amino-acid B-cell epitope NP_243–251 of the PR/8/34 virus.”

This created a synthetic multi-strain hybrid virus containing genetic components from at least four different influenza species—H1N1, H1N1pdm, H2N2, and influenza B.

Testing with Live H5N1 Challenge

The synthetic UniFluVec virus was later tested against one of the world’s most lethal avian influenza strains:

“Vaccination of ferrets was performed within a biological safety cabinet (BSC). On study day 0, animals were anesthetized and vaccinated IN with 1.0 ml (0.5 ml/nares) of the PBS (vehicle control) or vaccine virus.”

“On day 21 or 23, each ferret was anesthetized and infected IN with 1.0 ml (approximately 0.5 ml/nares) of influenza virus A/Indonesia/5/2005 (H5N1).”

Bottom Line

The NIH-funded research demonstrates that synthetic, multi-strain chimeric influenza viruses were genetically constructed in Europe using reverse-engineered plasmids and then tested in live mammals with an H5N1 challenge in the United States.

Taken together with concurrent projects at the USDA, CDC, and BARDA, the work underscores a broad, multi-agency program to bioengineer, test, and commercialize novel avian-influenza viruses and related countermeasures—often under the banner of “vaccine” or “therapeutic” development.

While the authors describe their study as vaccine research, the combination of cross-continental virus construction, high-pathogenicity live-animal challenges, and U.S. federal coordination situates it squarely within the domain of gain-of-function–type experimentation, raising renewed questions about oversight, transparency, and biosecurity.

The COVID-19 pandemic was likely the result of lab-engineered pathogen manipulation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA.

CDC Creates New Bird Flu Virus With Enhanced Immune System Evasion in Georgia Lab: Journal ‘npj Viruses’

U.S. gov’t makes pandemic-grade H5N1 avian influenza pathogen invisible to the immune system’s defenses—in just six days.

A new study published last month in npj Viruses describes how the U.S. Centers for Disease Control and Prevention (CDC) engineered a brand-new strain of bird flu in its Atlanta, Georgia laboratories.

The current head of the CDC is Jim O’Neil.

The risky research involved scientists from the CDC in Atlanta, the J. Craig Venter Institute (Rockville, MD, and La Jolla, CA), and the University of California San Diego.

Authors included Li Wang, Masato Hatta, Chenchen Feng, Paul Carney, Benjamin Rambo-Martin, Vivien G. Dugan, C. Todd Davis, James Stevens, Bin Zhou, and others—a team that directly manipulated the H5N1 virus using genetic engineering.

The COVID-19 pandemic was the result of lab-engineered pathogen creation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA—raising grave questions about why U.S. government scientists are once again creating novel, immune-evading strains of dangerous viruses inside federal laboratories.

The new study was published the same month U.S. President Donald Trump stood before the United Nations and called for an end to the creation of biological weapons, even as U.S. government labs like the CDC continue engineering deadly new pathogens under the banner of pandemic preparedness.Subscribe

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Why the CDC Says It Built a New Virus

In 2024, a Missouri patient was reported to be infected with an H5N1 virus carrying two unusual mutations in its surface protein (hemagglutinin).

Oddly, the CDC said it was unable to isolate a live virus from the sample.

To study it, the authors said they had to engineer a synthetic version of the Missouri virus by inserting the mutations into the backbone of a cattle-outbreak strain.

The paper itself says:

“Because virus isolation was unsuccessful, the generation of a recombinant virus carrying these substitutions was necessary…”

In other words, the CDC built this new H5N1 in the lab.

The government engineered a man-made disease-causing construct that had never been seen in nature before.

Where the Work Took Place

The study makes clear this was CDC-led work inside federal labs in Georgia:

“All experiments involving highly pathogenic avian influenza (HPAI) A(H5N1) viruses were conducted in Biosafety Level 3 enhanced (BSL-3E) or Animal Biosafety Level 3 (ABSL-3) laboratories at the U.S. Centers for Disease Control and Prevention (CDC), including enhancements required by the U.S. Department of Agriculture and the Federal Select Agent Program.”

This confirms the location (Atlanta, Georgia) and the agency (CDC) responsible.

What the Mutations Did

Two mutations were introduced: P136S and A156T.

The most important one is A156T, which changed how the virus interacts with the immune system.

The study admits:

“The HA P136S/A156T substitutions altered the antigenicity of the 2.3.4.4b A(H5N1) virus, most likely through the introduction of an N-linked glycosylation site at residue 154 enabled by the A156T substitution. This glycosylation likely shields antigenic site B from antibody recognition, resulting in reduced HI and neutralization titers…”

This means the virus was said to have gained a new sugar coating at residue 154, which acted like a shield, hiding it from antibodies that would normally detect it.

Immune Evasion Results

The effect was dramatic and alarming.

Antibodies that normally neutralize H5N1 were far less effective against the engineered virus.

The study shows:

“Introduction of the A156T substitution led to at least a 4-fold reduction in HI titers for all antisera… In the neutralization assay, antisera to TX37 and MI90 showed significantly reduced neutralizing activity against viruses carrying the A156T substitution.”

That means antibodies were four times less effective at minimum, and in some tests, over 99% less effective at neutralizing the new virus.

Put plainly: CDC gave H5N1 a mutation that made it invisible to the immune system’s defenses.

Speed of Engineering

One of the most startling admissions is how quickly the CDC created this recombinant bird flu:

“From the time the partial HA sequence was obtained on September 13, 2024, to the completion of plasmid construction, virus rescue, and the first HI results on September 23, only 10 calendar days (6 business days) had elapsed.”

In other words, within 10 days, the CDC had gone from partial genetic data to a fully functional, lab-built H5N1 virus.

This shows just how rapidly government labs can create new pandemic-grade pathogens.

Bottom Line

The CDC admits in its own paper that it engineered a new strain of H5N1 bird flu in its Georgia labs—a strain that had never existed in nature.

The stated purpose was to study two mutations (P136S and A156T) found in a human patient.

One of those mutations, A156T, created a sugar shield that dramatically reduced antibody recognition, in some cases by more than 99%.

Federal scientists demonstrated, and published, that they can build new, immune-evading strains of one of the world’s deadliest viruses in a matter of days.

That is the very description of gain-of-function experimentation—and it was funded and carried out by the CDC itself.

USDA, NIH, NIAID Fund Creation of Lab-Engineered Bird Flu Viruses With Enhanced Growth and Replication Traits in Nebraska

After Trump calls for ending bioweapons creation.

The U.S. Department of Agriculture (USDA) and the National Institutes of Health (NIH)—specifically its National Institute of Allergy and Infectious Diseases (NIAID)—have funded scientists at the University of Nebraska–Lincoln to create brand-new, never-before-seen influenza viruses through laboratory engineering, according to a September 21 preprint posted on bioRxiv.

The authors claim their aim was vaccine development, but the methods reveal the deliberate construction of novel pathogens with enhanced laboratory growth traits.

The COVID-19 pandemic was the result of lab-engineered pathogen creation, according to Congress, the White House, the Department of Energy, the FBI, and the CIA.

The revelation of this federally funded creation of novel pathogens on American soil comes just days after President Donald Trump stood before the United Nations calling for (here) a global end to bioweapons research, raising profound questions about whether “vaccine development” is now serving as the cover for the very gain-of-function experiments he condemned.

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Stated Aim: A New Vaccine for Cattle

The paper frames its purpose around the 2024 detection of H5N1 bird flu in U.S. dairy herds and the lack of licensed cattle vaccines.

The authors present their work as an effort to design a “centralized consensus H5 vaccine” delivered with adenovirus vectors, hoping to elicit both systemic and mucosal immunity in calves.

They argue that such a vaccine would reduce agricultural losses and “remove cattle as a newly established reservoir for zoonotic spread” of bird flu.

Yet beneath the stated goal of protecting cattle lies the undeniable reality that U.S. tax dollars are being used to build entirely new influenza strains in the lab—dangerous, pandemic-causing pathogens created under the banner of “vaccine development.”

What They Actually Did: Built New Viruses That Never Existed in Nature

Instead of working with purportedly circulating H5N1 isolates, the team engineered new pathogens using reverse genetics:

• Six internal gene segments (PB1, PB2, PA, NP, M, and NS) were pulled from the PR8 H1N1 laboratory strain, which is optimized for high replication in mammalian cells and chicken eggs.
• These were combined with synthetic H5 and N genes stripped of their natural multibasic cleavage site.
• The result: novel reassortant influenza viruses with enhanced lab replication efficiency compared to wild-type H5N1.

The viruses were generated in HEK293 and MDCK cells, then amplified in embryonated chicken eggs, all under BSL-2 laboratory conditions at the University of Nebraska–Lincoln.

Enhanced Growth and Replication Traits

By design, the engineered viruses gained new functions not seen in nature:

• Enhanced growth efficiency in eggs and mammalian cells from the PR8 backbone.
• Streamlined replication for lab handling.
• BSL-2 compatibility, expanding the number of facilities able to handle them.

Who Did the Work

• Joshua Wiggins
• Adthakorn Madapong
• Eric A. Weaver (corresponding author).

All three are affiliated with the Nebraska Center for Virology and the School of Biological Sciences at the University of Nebraska–Lincoln.

Where It Was Done

• Genetic engineering, reverse genetics virus creation, and animal studies were all performed at the University of Nebraska–Lincoln, under IBC and IACUC approvals.
• Work was conducted in BSL-2+ labs, required only for moderate-risk agents, despite the fact that the study involved the creation of novel influenza viruses capable of causing pandemics.

Who Paid for It

• USDA National Institute of Food and Agriculture (NIFA), Agriculture and Food Research Initiative (Grant Nos. 2020-06448, 2024-08723).
• NIH – NIAID (Grant No. 1R01AI147109).

Bombshell Details

• Replication-Competent Vectors: The study used replication-competent adenovirus vaccine platforms (Ad28 and Ad48) that can spread within the host, unlike safer replication-deficient types.
• Failed Protection Against the Actual Threat: Despite claims of vaccine promise, the engineered vaccine produced no protective neutralization against the circulating bovine H5N1 strain (Bovine/24)—the virus causing real outbreaks in U.S. cattle.
• No Cattle Challenge Studies: The vaccine was never tested against live infection in cattle, only in mice.
• Sex Bias: Only male calves were tested, ignoring potential sex differences in immune response. By testing only male calves, the study ignored well-established sex differences in immunity—females typically mount stronger antibody and T-cell responses but also suffer higher rates of adverse reactions—leaving half the population unaccounted for and casting doubt on the safety and applicability of the findings.

Bottom Line

While the University of Nebraska team presented their work as vaccine development, the methods show they constructed brand-new bird flu viruses through reverse genetics, engineered with a PR8 laboratory backbone to enhance replication traits.

These pathogens, created with federal funding, were built and amplified under BSL-2 conditions—labs designed for moderate-risk microbes, not novel influenza strains with pandemic potential.

The authors claim their goal was to stop the spread of H5N1 in cattle, but the vaccine failed to neutralize the very strain now circulating in U.S. herds, was never tested in cattle challenges, and excluded females altogether.

Coming just days after President Trump’s UN call to end bioweapons creation, this project exemplifies the dangerous reality that pandemic-capable pathogens are being created under the guise of “vaccine development.”

On American soil.

With American tax dollars.

Sound familiar?